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Transition metal amino acid complexes are a large family of coordination complexes containing the conjugate bases of the amino acids, the 2-aminocarboxylates. Amino acids are prevalent in nature, and all of them function as ligands toward the transition metals. [ 1 ]
Binding of metal ions via chelation is usually achieved via histidines or cysteines. In some cases this is a necessary part of their folding and maintenance of a tertiary structure. Alternatively, a metal-binding protein may maintain its structure without the metal (apo form) and bind it as a ligand (e.g. as part of metal homeostasis).
The two amino acid residues are linked through a peptide bond. As both the amine and carboxylic acid groups of amino acids can react to form amide bonds, one amino acid molecule can react with another and become joined through an amide linkage. This polymerization of amino acids is what creates proteins.
Some "minerals" are essential for life, but most are not. [1] [2] [3] Minerals are one of the four groups of essential nutrients; the others are vitamins, essential fatty acids, and essential amino acids. [4] The five major minerals in the human body are calcium, phosphorus, potassium, sodium, and magnesium. [2]
This is a list of minerals which have Wikipedia articles. Minerals are distinguished by various chemical and physical properties. Differences in chemical composition and crystal structure distinguish the various species .
As of November 2024, the IMA - CNMNC List of Minerals lists 6,100 valid minerals, including 1,153 pre-IMA minerals (grandfathered), and 97 questionable minerals. [2] Also as of November 2024 [update] , the Mineralogical Society of America's Handbook of Mineralogy lists 5,663 species, [ 3 ] and the IMA Database of Mineral Properties/RRUFF ...
The abundance of metal binding proteins may be inherent to the amino acids that proteins use, as even artificial proteins without evolutionary history will readily bind metals. [8] Most metals in the human body are bound to proteins. For instance, the relatively high concentration of iron in the human body is mostly due to the iron in hemoglobin.
The oxide mineral class includes those minerals in which the oxide anion (O 2−) is bonded to one or more metal alloys. The hydroxide-bearing minerals are typically included in the oxide class. Minerals with complex anion groups such as the silicates, sulfates, carbonates and phosphates are classed separately.