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Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. [1] Tentative evidence has found other antibiotics to be more effective, and therefore it is no longer generally recommended for second-degree (partial-thickness) burns, but is still ...
Silver sulfadiazine (SSD) is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. [4] [21] It was discovered in the 1960s, [22] and was the standard topical antimicrobial for burn wounds for decades. [23] [24]
It is a second-line treatment for otitis media, prophylaxis of rheumatic fever, chancroid, chlamydia, and infections by Haemophilus influenzae. [1] It is also used as adjunct therapy for chloroquine-resistant malaria and several forms of bacterial meningitis. [4] It is taken by mouth. [1] Sulfadiazine is available in multiple generic tablets of ...
The plasma concentration reached a steady state on Day 5 of repeated administration study when nadifloxacin 1% cream was applied at 5 g twice daily to normal healthy individuals for a period of 7 days. The plasma concentration reached a peak of 4.1 ng/ml at 8 hours post-final dosing with an elimination half-life of 23.2 hours.
The product of fusB-type resistance genes is a 213-residue cytoplasmic protein which interacts in a 1:1 ratio with EF-G. FusB-type proteins bind in a region distinct from fusidic acid to induce a conformational change which results in liberation of EF-G from the ribosome, allowing the elongation factor to participate in another round of ...
Sulfathiazole is an organosulfur compound used as a short-acting sulfa drug. [1] Formerly, it was a common oral and topical antimicrobial, until less toxic alternatives were discovered. [2] Sulfathiazole exists in various forms . The imine tautomer is dominant in solid samples. [3]
Silver nitrate has not been thoroughly investigated for potential carcinogenic effect. [29] Silver nitrate is currently unregulated in water sources by the United States Environmental Protection Agency. However, if more than 1 gram of silver is accumulated in the body, a condition called argyria may develop. Argyria is a permanent cosmetic ...
Gentamicin/betamethasone valerate/clotrimazole is a fixed dose combination veterinary drug, sold under the trade name Otomax. [1] It is a suspension for otic use in dogs. The active ingredients are gentamicin, betamethasone valerate and clotrimazole. This drug product is used for treatment of acute external otitis. It is also used for the ...
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