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Bronchiolitis obliterans results in worsening shortness of breath, wheezing, and a dry cough.The symptoms can start gradually, or severe symptoms can occur suddenly. [9] [10] These symptoms represent an obstructive pattern that is non-reversible with bronchodilator therapy, and need to be related to various lung insults. [11]
Cryptogenic organizing pneumonia; Other names: Bronchiolitis obliterans with organizing pneumonia, idiopathic interstitial pneumonia [1]: Micrograph showing a Masson body (off center left/bottom of the image – pale circular and paucicellular), as may be seen in cryptogenic organizing pneumonia.
Vaping-associated pulmonary injury (VAPI), [4] also known as vaping-associated lung injury (VALI) [1] or e-cigarette, or vaping, product use associated lung injury (E/VALI), [2] [a] is an umbrella term, [15] [16] used to describe lung diseases associated with the use of vaping products that can be severe and life-threatening. [3]
[142] A 2014 case report observed the correlation between sub-acute bronchiolitis and vaping. [137] After quitting vaping the symptoms improved. [137] Vaping causes bronchospasm. [102] Adolescents who vaped had a higher frequency of chronic bronchitis symptoms. [143] The long-term effects regarding respiratory flow resistance are unknown. [97]
A February 2022 research article on vape aerosol from JUUL products showed "Profound pathological changes to upper airway, lung tissue architecture, and cellular structure," of mice exposed for as little as 9 weeks. "This vaping-induced pulmonary injury model demonstrates mechanistic underpinnings of vaping-related pathologic injury." [90]
Respiratory bronchiolitis is a lung disease associated with tobacco smoking. [1] In pathology, it is defined by the presence of " smoker's macrophages ". [ 1 ] When manifesting significant clinical symptoms it is referred to as respiratory bronchiolitis interstitial lung disease (RB-ILD).
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Ventilator-associated pneumonia (VAP) is a type of lung infection that occurs in people who are on mechanical ventilation breathing machines in hospitals. As such, VAP typically affects critically ill persons that are in an intensive care unit (ICU) and have been on a mechanical ventilator for at least 48 hours.