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Mitotic cell division enables sexually reproducing organisms to develop from the one-celled zygote, which itself is produced by fusion of two gametes, each having been produced by meiotic cell division. [5] [6] After growth from the zygote to the adult, cell division by mitosis allows for continual construction and repair of the organism. [7]
All living cells arise from pre-existing cells by division. The cell is the fundamental unit of structure and function in all living organisms. [14] The activity of an organism depends on the total activity of independent cells. [15] Energy flow (metabolism and biochemistry) occurs within cells. Cells contain DNA which is found specifically in ...
The cell cycle, or cell-division cycle, is the sequential series of events that take place in a cell that causes it to divide into two daughter cells. These events include the growth of the cell, duplication of its DNA ( DNA replication ) and some of its organelles , and subsequently the partitioning of its cytoplasm, chromosomes and other ...
[11] [12] Miller and his co-workers (1954) isolated and purified the cell division substance in crystallised form from autoclaved herring fish sperm DNA. [11] This active compound was named as Kinetin because of its ability to promote cell division and was the first cytokinin to be named. Kinetin was later identified to be 6-furfuryl-amino purine.
Cytokinesis (/ ˌ s aɪ t oʊ k ɪ ˈ n iː s ɪ s /) is the part of the cell division process and part of mitosis during which the cytoplasm of a single eukaryotic cell divides into two daughter cells. Cytoplasmic division begins during or after the late stages of nuclear division in mitosis and meiosis.
DNA damage is the main indication for a cell to "restrict" and not enter the cell cycle. The decision to commit to a new round of cell division occurs when the cell activates cyclin-CDK-dependent transcription which promotes entry into S phase. This check point ensures the further process. [10]
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The G 1 phase, gap 1 phase, or growth 1 phase, is the first of four phases of the cell cycle that takes place in eukaryotic cell division. In this part of interphase, the cell synthesizes mRNA and proteins in preparation for subsequent steps leading to mitosis. G 1 phase ends when the cell moves into the S phase of interphase.