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Like Δ 9-THC, 11-hydroxy-THC is a partial agonist at the cannabinoid receptor CB 1, but with significantly higher binding affinity (K i = 0.37 nM compared to Δ 9-THC K i = 35 nM). [7] With respect to cAMP inhibition at CB 1 it displays a similar efficacy to that of Δ 9 -THC (EC 50 = 11 nM vs. EC 50 = 5.2 nM, respectively), but a lower ...
THC and its 11-OH-THC and THC-COOH metabolites can be detected and quantified in blood, urine, hair, oral fluid or sweat using a combination of immunoassay and chromatographic techniques as part of a drug use testing program or in a forensic investigation. [57] [58] [59] There is ongoing research to create devices capable of detecting THC in ...
Cannabis indica is an annual plant species in the family Cannabaceae [1] indigenous to the Hindu Kush mountains of Southern Asia. [2] The plant produces large amounts of tetrahydrocannabinol (THC) [ 3 ] and tetrahydrocannabivarin (THCV), with total cannabinoid levels being as high as 53.7%. [ 4 ]
THC is just one of more than 100 identified cannabinoid compounds in Cannabis, which also include cannabinol (CBN) and cannabidiol (CBD). Cannabis plants vary widely, with different strains producing dynamic balances of cannabinoids (THC, CBD, etc.) and yielding markedly different effects. Popular strains are often hybrids of C. sativa and C ...
THC, the main psychoactive component of cannabis, may only be detectable in saliva and oral fluid for 2–24 hours in most cases. [8] [9] The main metabolite excreted in the urine is 11-Nor-9-carboxy-THC, also known as THC-COOH. Most cannabis drug tests yield a positive result when the concentration of THC-COOH in urine exceeds 50 ng/mL. [10]
Cannabis strains is a popular name to refer to plant varieties of the monospecific genus Cannabis sativa L.. They are either pure or hybrid varieties of the plant, which encompasses various sub-species C. sativa , C. indica , and C. ruderalis .
2 Abstract Although recent legislation has been enacted to require fast-food restaurants to display calorie information on menus, the consequences of posting such information remain unclear.
Δ-10-Tetrahydrocannabinol (Delta-10-THC, Δ 10-THC, alternatively numbered as Δ 2-THC) is a positional isomer of tetrahydrocannabinol, discovered in the 1980s.Two epimers have been reported in the literature, with the 9-methyl group in either the (R) or (S) conformation; of these, the (R) epimer appears to be the more active isomer as well as the double bond in the 10th position instead of ...