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Methylecgonidine (anhydromethylecgonine; anhydroecgonine methyl ester; AEME) is a chemical intermediate derived from ecgonine or cocaine.. Methylecgonidine is a pyrolysis product formed when crack cocaine is smoked, making this substance a useful biomarker to specifically test for use of crack cocaine, as opposed to powder cocaine which does not form methylecgonidine as a metabolite. [1]
Trituration of the free base from cocaine hydrochloride (or "cooking") is done by dissolving the cocaine hydrochloride in water over constant heat, while simultaneously adding a base (such as baking soda) to form the free base cocaine. The free base of cocaine forms a solid "rock", pieces of which can be smoked directly (crack cocaine). [4]
Chemical structure of cocaine. The biosynthesis of cocaine has long attracted the attention of biochemists and organic chemists. This interest is partly motivated by the strong physiological effects of cocaine, but a further incentive was the unusual bicyclic structure of the molecule. The biosynthesis can be viewed as occurring in two phases ...
[5] [6] Coca leaves were used in Coca-Cola's preparation; the small amount of cocaine they contained – along with caffeine originally sourced from kola nuts – provided the drink's "tonic" quality. [6] [7] In 1903, cocaine was removed, leaving caffeine as the sole stimulant ingredient, and all medicinal claims were dropped.
Drug precursors, also referred to as precursor chemicals or simply precursors, are substances used to manufacture illicit drugs. Most precursors also have legitimate commercial uses and are legally used in a wide variety of industrial processes and consumer products, such as medicines, flavourings, and fragrances.
In South America, coca paste, also known as cocaine base and, therefore, often confused with cocaine sulfate in North America, is relatively inexpensive and is widely used by low-income consumers. The coca paste is smoked in tobacco or cannabis cigarettes and use has become widespread in several Latin American countries.
How does pink cocaine affect someone? It can be hard to determine how the drug cocktail may affect someone after ingesting it. WebMD said this is due to several factors: the types of drugs mixed ...
In 2005, scientists found surprisingly large quantities of benzoylecgonine in Italy's Po River and used its concentration to estimate the number of cocaine users in the region. [4] In 2006, a similar study was performed in the Swiss ski town of Saint-Moritz using wastewater to estimate the daily cocaine consumption of the population. [ 5 ]