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Enoxaparin sodium, sold under the brand name Lovenox among others, is an anticoagulant medication (blood thinner). [11] It is used to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) including during pregnancy and following certain types of surgery. [ 11 ]
Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]
Apart from using unfractionated heparin instead, it may be possible to reduce the dose and/or monitor the anti-Xa activity to guide treatment. [3] The most common side effects include bleeding, which could be severe or even fatal, allergic reactions, injection site reactions, and increases in liver enzyme tests, usually without symptoms. [13]
The guideline directs that medications should be given at regular intervals ("by the clock") so that continuous pain relief occurs, and ("by the individual") dosing by actual relief of pain rather than fixed dosing guidelines. It recognizes that breakthrough pain may occur and directs immediate rescue doses be provided.
An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.
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enoxaparin: anticoagulant activation of antiprothrombin, prevents fibrin formation slow IV platelet count is monitored [45] [41] dalteparin: anticoagulant activation of antiprothrombin, prevents fibrin formation IV [41] fondaparinux: anticoagulant inhibits thrombin production injection aspirin not recommended with this medication [41] [24] [2 ...
A decades-old cosmetic procedure called mesotherapy, which involves injecting unregulated mixtures of vitamins and drugs under the skin to reduce under-eye bags, is regaining popularity in the US.
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