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Drug precursors, also referred to as precursor chemicals or simply precursors, are substances used to manufacture illicit drugs. Most precursors also have legitimate commercial uses and are legally used in a wide variety of industrial processes and consumer products, such as medicines, flavourings, and fragrances.
In South America, coca paste, also known as cocaine base and, therefore, often confused with cocaine sulfate in North America, is relatively inexpensive and is widely used by low-income consumers. The coca paste is smoked in tobacco or cannabis cigarettes and use has become widespread in several Latin American countries.
[28] [41] [42] Its negative effects such as anxiety, headaches, and appetite loss are likely mediated by its actions on the 5-HT 2C receptor. [ 13 ] [ 24 ] [ 43 ] Other effects of mCPP include nausea , hypoactivity , and penile erection , the latter two the result of increased 5-HT 2C activity and the former likely via 5-HT 3 stimulation.
Coca-Cola used coca leaf extract in its products from 1885 until about 1903, when it began using decocainized leaf extract. [9] [10] [11] Extraction of cocaine from coca requires several solvents and a chemical process known as an acid–base extraction, which can fairly easily extract the alkaloids from the plant.
An analysis of 41 different synthetic cannabis mimic blends sold commercially in New Zealand, conducted by the Institute of Environmental Science and Research and released in July 2011, found 11 different synthetic cannabinoid ingredients used, including JWH-018, JWH-073, AM-694, AM-2201, RCS-4, RCS-4 butyl homologue, JWH-210, JWH-081, JWH-250 ...
Psychoactive and psychotropic are often used interchangeably in general and academic sources, to describe substances that act on the brain to alter cognition and perception; some sources make a distinction between the terms. One narrower definition of psychotropic refers to drugs used to treat mental disorders, such as anxiolytic sedatives ...
At higher doses they may result in slurred speech, staggering gait, poor judgment, and slow, uncertain reflexes. Doses of sedatives such as benzodiazepines, when used as a hypnotic to induce sleep, tend to be higher than amounts used to relieve anxiety, whereas only low doses are needed to provide a peaceful effect.
It is commonly used in Arab cultures as relief medication for headaches or as a performance enhancer. The derived chemical Ambrein increases testosterone concentrations, triggering sexual desire and sexual behavior, but in animal studies only. Further research is needed to know the effects in humans.
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