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Benzyl isothiocyanate, and other isothiocyanates in general, were found to be protective against pancreatic carcinogenesis in vitro [3] via expression of the p21/WAF1 gene. [4] A recent published study showed its restraining impact on obesity, fatty liver, and insulin resistance in diet-induced obesity mouse model.
In organic chemistry, isothiocyanate is a functional group as found in compounds with the formula R−N=C=S. Isothiocyanates are the more common isomers of thiocyanates , which have the formula R−S−C≡N .
The main complication with this route is the competing formation of alkyisothiocyanates. "SN1-type" substrates (e.g., benzyl halides) tend to give the isothiocyanate derivatives. Some organic thiocyanates are generated by cyanation of some organosulfur compounds.
The isothiocyanate further decomposes into hydroxybenzyl alcohols with the release of thiocyanates. [1] [2] [3] In the presence of a nitrile-specifier protein, the less toxic 4-hydroxyphenylacetonitrile is formed from the mustard oil glycoside instead. The cabbage butterfly exploits this mechanism to avoid the toxic effects of the ...
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Finland handed the defending champion United States its first loss at the 2025 world junior hockey championship as Tuomas Uronen scored in overtime for a 4-3 win on Sunday afternoon.
Still, Trump's nomination of Scott Bessent to the top Treasury post raised hopes that tariffs will be more measured. And with only 21 trading days left in the year, analysts, investors, and market ...
But the U.S. drug treatment system — which is mostly a hodgepodge of abstinence-only and 12-step-based facilities that resemble either minimum-security prisons or tropical spas — has for the most part ignored the medical science and been slow to embrace medication-assisted treatment, as The Huffington Post reported in January. As a result ...