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  2. Cryoprecipitate - Wikipedia

    en.wikipedia.org/wiki/Cryoprecipitate

    Cryoprecipitate, also called cryo for short, or Cryoprecipitate Antihemophilic factor (AHF), is a frozen blood product prepared from blood plasma. [1] To create cryoprecipitate, Plasma is slowly thawed to 1–6 °C. A cold-insoluble precipitate is formed, which is collected by centrifugation, resuspended in a small amount of residual plasma ...

  3. Cryofibrinogenemia - Wikipedia

    en.wikipedia.org/wiki/Cryofibrinogenemia

    Cryofibrinogenemia refers to a condition classified as a fibrinogen disorder in which a person's blood plasma is allowed to cool substantially (i.e. from its normal temperature of 37 °C to the near-freezing temperature of 4 °C), causing the (reversible) precipitation of a complex containing fibrinogen, fibrin, fibronectin, and, occasionally, small amounts of fibrin split products, albumin ...

  4. Cryosupernatant - Wikipedia

    en.wikipedia.org/wiki/Cryosupernatant

    The term cryosupernatant (also called cryo-poor plasma, cryoprecipitate depleted, cryoprecipitate reduced plasma) refers to plasma from which the cryoprecipitate has been removed. It is used to treat thrombocytopenic purpura .

  5. Cohn process - Wikipedia

    en.wikipedia.org/wiki/Cohn_process

    The continuous-flow preparation of cryoprecipitate was subsequently integrated into the process upstream of Cohn Fractionation. [ 13 ] Nevertheless, this process still serves as a major foundation for the blood industry in general and its influence can be seen as it is referred to in the development of newer methods.

  6. Fibrinogen deficiency - Wikipedia

    en.wikipedia.org/wiki/Fibrinogen_deficiency

    The most common type of treatment is cryoprecipitate a fibrinogen concentrate used in a drip to increase fibrinogen levels to normal during surgical procedures or after trauma. [11] [2] RiaSTAP, a factor I concentrate, was approved by the U.S. FDA in 2009 for use when the fibrinogen level was below 50 mg/deciliter of plasma. [12]

  7. Blood plasma - Wikipedia

    en.wikipedia.org/wiki/Blood_plasma

    For example, when blood pressure drops in circulatory shock, Starling forces drive fluid into the interstitium, causing third spacing. [11] Standing still for a prolonged period will cause an increase in transcapillary hydrostatic pressure. As a result, approximately 12% of blood plasma volume will cross into the extravascular compartment.

  8. Fresh frozen plasma - Wikipedia

    en.wikipedia.org/wiki/Fresh_frozen_plasma

    Fresh frozen plasma (FFP) is a blood product made from the liquid portion of whole blood. [3] It is used to treat conditions in which there are low blood clotting factors (INR > 1.5) or low levels of other blood proteins. [3] [1] It may also be used as the replacement fluid in plasma exchange.

  9. Dysfibrinogenemia - Wikipedia

    en.wikipedia.org/wiki/Dysfibrinogenemia

    Fibrinogen is a glycoprotein made and secreted into the blood primarily by liver hepatocyte cells. Endothelium cells also make what appears to be small amounts of fibrinogen but this fibrinogen has not been fully characterized; blood platelets and their precursors, bone marrow megakaryocytes, although once thought to make fibrinogen, are now known to take up and store but not make the ...

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