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The gastric folds (or gastric rugae) are coiled sections of tissue that exist in the mucosal and submucosal layers of the stomach. [1] They provide elasticity by allowing the stomach to expand when a bolus enters it. These folds stretch outward through the action of mechanoreceptors, which respond to the increase in pressure. [2]
In anatomy, rugae (sg.: ruga) are a series of ridges produced by folding of the wall of an organ. [1] In general, rugae are a biological feature found in many organisms, serving purposes such as increasing surface area, flexibility, or structural support. Most commonly rugae refers to the gastric rugae of the internal surface of the stomach.
The gastric mucosa is the mucous membrane layer of the stomach, ... During the contracted state of the stomach it is thrown into numerous folds or rugae, which, ...
In the stomach, the epithelium is simple columnar, and is organised into gastric pits and glands to deal with secretion. [1] In the small intestine, epithelium is simple columnar and specialised for absorption. It is organised into plicae circulares and villi, and the enterocytes have microvilli.
The stomach is involved in the gastric phase of digestion, following the cephalic phase in which the sight and smell of food and the act of chewing are stimuli. In the stomach a chemical breakdown of food takes place by means of secreted digestive enzymes and gastric acid. The stomach is located between the esophagus and the small intestine.
Ménétrier disease is a rare, acquired, premalignant disease of the stomach characterized by massive gastric folds, excessive mucus production with resultant protein loss, and little or no acid production (achlorhydria). The disorder is associated with excessive secretion of transforming growth factor alpha (TGF-α). [1]
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus.The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines.
The greater curvature of the stomach forms the lower left or lateral border of the stomach. [3] Starting from the cardiac orifice it begins at the cardiac notch, forming an arch backward, upward, and to the left. A horizontal plane across from the cardiac notch encloses an area called the fundus of the stomach.