Search results
Results from the WOW.Com Content Network
The amygdala, cerebellum, and many other brain regions have been implicated in autism. [15]Unlike some brain disorders which have clear molecular hallmarks that can be observed in every affected individual, such as Alzheimer's disease or Parkinson's disease, autism does not have a unifying mechanism at the molecular, cellular, or systems level.
Rett syndrome brain samples and autism brain samples show immaturity of dendrite spines and reduction of cell-body size due to errors in coupled regulation between MECP2 and EGR2. [62] However, because of the multigene involvement in autism, the MECP2 gene has only been identified as a vulnerability factor in autism. [63]
Iryna Spodarenko / GettyWe’ve come a long way in our understanding of autism since it was first used as a clinical description in 1943. Scientists have identified some of the genes that seem to ...
The severity of symptoms and functional impairment vary between individuals. [3] There are many known environmental, genetic, and biological causes of autism. Research indicates that genetic factors predominantly contribute to its appearance. The heritability of autism is complex and many of the genetic interactions involved are unknown. [1]
The stria terminalis (or terminal stria) is a structure in the brain consisting of a band of fibers running along the lateral margin of the ventricular surface of the thalamus. Serving as a major output pathway of the amygdala , the stria terminalis runs from its centromedial division to the ventromedial nucleus of the hypothalamus .
The striatum (pl.: striata) or corpus striatum [5] is a cluster of interconnected nuclei that make up the largest structure of the subcortical basal ganglia. [6] The striatum is a critical component of the motor and reward systems; receives glutamatergic and dopaminergic inputs from different sources; and serves as the primary input to the rest of the basal ganglia.
Of the PDDs, Asperger syndrome was closest to classic autism in signs and likely causes; Rett syndrome and childhood disintegrative disorder share several signs with it, but were understood to potentially have unrelated causes; PDD not otherwise specified (PDD-NOS; also called atypical autism) was diagnosed when the criteria were not met for ...
Autism spectrum disorder [a] (ASD), or simply autism, is a neurodevelopmental disorder "characterized by persistent deficits in social communication and social interaction across multiple contexts" and "restricted, repetitive patterns of behavior, interests, or activities". [11] Sensory abnormalities are also included in the diagnostic manuals ...