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Developmental toxicity is any developmental malformation that is caused by the toxicity of a chemical or pathogen. It is the structural or functional alteration, reversible or irreversible, which interferes with homeostasis , normal growth , differentiation , development or behavior.
An early life stage (ELS) test is a chronic toxicity test using sensitive early life stages like embryos or larvae to predict the effects of toxicants on organisms. [1] ELS tests were developed to be quicker and more cost-efficient than full life-cycle tests, taking on average 1–5 months to complete compared to 6–12 months for a life-cycle test.
The Bayley Scales of Infant and Toddler Development (version 4 was released September 2019) is a standard series of measurements originally developed by psychologist Nancy Bayley used primarily to assess the development of infants and toddlers, ages 1–42 months. [1]
Teratology is the study of abnormalities of physiological development in organisms during their life span. It is a sub-discipline in medical genetics which focuses on the classification of congenital abnormalities in dysmorphology caused by teratogens and also in pharmacology and toxicology.
The Gesell Developmental Schedules are a set of developmental metrics which outline the ages & stages of development in young children developed by Dr. Arnold Gesell and colleagues. [1] The original scale is generally considered not to satisfy the standards of rigor currently accepted in the field of psychometrics and is no longer used as an ...
The Denver II is available in various languages. Videotapes and two manuals describe 14 hours of structured instruction and recommend testing a dozen children for practice. Beyond this a professional degree is not required. As with all developmental testing, one must follow the instructions in detail. [8]
Toxicology testing, also known as safety assessment, or toxicity testing, is the process of determining the degree to which a substance of interest negatively impacts the normal biological functions of an organism, given a certain exposure duration, route of exposure, and substance concentration.
Baroda Developmental Screening Test is a screening test for motor-mental assessment of infants, developed from Bayley Scales of Infant Development. [ 1 ] History