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Illustration depicting the layers of the heart wall including the innermost endocardium. The endocardium (pl.: endocardia) is the innermost layer of tissue that lines the chambers of the heart.
The endocardial cushions are thought to arise from a subset of endothelial cells that undergo epithelial-mesenchymal transition, a process whereby these cells break cell-to-cell contacts and migrate into the cardiac jelly (towards the interior of the heart tube). These migrated cells form the "swellings" called the endocardial cushions seen in ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 24 February 2025. List of organ systems in the human body Part of a series of lists about Human anatomy General Features Regions Variations Movements Systems Structures Arteries Bones Eponymous Foramina Glands endocrine exocrine Lymphatic vessels Nerves Organs Systems Veins Muscles Abductors Adductors ...
The endocardial tubes have an intimate proximity to the foregut or pharyngeal endoderm. [1] As folding of the embryo in the horizontal plane initiates in the 4th week of gestation, the endocardial tubes meet in the midline to form the primitive heart tube, which will eventually develop into the histologically definitive endocardium.
This begins with the formation of two endocardial tubes which merge to form the tubular heart, also called the primitive heart tube. The heart is the first functional organ in vertebrate embryos . The tubular heart quickly differentiates into the truncus arteriosus , bulbus cordis , primitive ventricle , primitive atrium , and the sinus venosus .
In humans, the heart is approximately the size of a closed fist and is located between the lungs, in the middle compartment of the chest, called the mediastinum. [4] In humans, the heart is divided into four chambers: upper left and right atria and lower left and right ventricles.
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. [1] [2] It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek kardia meaning heart, and Latin vascula meaning vessels).
When referring to endocardial luminal distances, it is EDD minus ESD divided by EDD (times 100 when measured in percentage). [25] Normal values may differ somewhat dependent on which anatomical plane is used to measure the distances. Normal range is 25–45%, Mild is 20–25%, Moderate is 15–20%, and Severe is <15%. [26]