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Autism was found to occur more often in families of physicists, engineers and scientists. 12.5% of the fathers and 21.2% of the grandfathers (both paternal and maternal) of children with autism were engineers, compared to 5% of the fathers and 2.5% of the grandfathers of children with other syndromes. [47] Other studies have yielded similar ...
Autism spectrum disorder [a] (ASD), or simply autism, is a neurodevelopmental disorder "characterized by persistent deficits in social communication and social interaction across multiple contexts" and "restricted, repetitive patterns of behavior, interests, or activities". [11] Sensory abnormalities are also included in the diagnostic manuals ...
A common presentation of sleep apnea in children with autism is insomnia. [67] All known genetic syndromes which are linked to autism have a high prevalence of sleep apnea. The prevalence of sleep apnea in Down's Syndrome is 50% - 100%. [68] Sleep problems and OSA in this population have been linked to language development. [69]
Altered habituation processes have been linked to characteristic traits of ASD, such as under-responsiveness to some stimuli and over-responsiveness to others. [22] There are many genetic and epigenetic factors that can contribute to increased excitability, but one of the mechanisms implicated in ASD is alterations in GABAergic systems in the ...
This approach to genetic association studies is largely atheoretical, and typically not guided by a particular biological hypothesis regarding the phenotype. [33] Genetic association findings for behavioural traits and psychiatric disorders have been found to be highly polygenic (involving many small genetic effects).
Autism is associated with several genetic disorders, [4] perhaps due to an overlap in genetic causes. [5] About 10–15% of autism cases have an identifiable Mendelian (single-gene) condition, chromosome abnormality, or other genetic syndrome, [6] a category referred to as syndromic autism.
The term "high-functioning autism" was used in a manner similar to Asperger syndrome, another outdated classification.The defining characteristic recognized by psychologists was a significant delay in the development of early speech and language skills, before the age of three years. [12]
Signs of autism are highly variable, and different individuals will have a different mix of traits. Some more common traits include: Avoidance of eye contact – preference to avoid eye contact and feelings of fear or being overwhelmed when looking into someone's eyes; Developmental delay – slower acquisition of life skills