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5-HTP is produced from the amino acid tryptophan through the action of the enzyme tryptophan hydroxylase. Tryptophan hydroxylase is one of the biopterin-dependent aromatic amino acid hydroxylases. Production of 5-HTP is the rate-limiting step in 5-HT (serotonin) synthesis. 5-HTP is normally rapidly converted to 5-HT by amino acid decarboxylase. [1]
MDMA is an empathogenic-entactogenic and serotonergic psychotropic drug used primarily for recreational, though sometimes also therapeutic, purposes.Among users of MDMA, the serotonergic effects of the drug are often of particular interest and concern: After consuming MDMA, serotonin concentrations are greatly reduced in the brain. 5-HTP is necessary for serotonin production and its ...
Changed unsupported conclusion in 3rd para of this section from, "5-HTP can cause hypertension by increasing plasma renin activity", to "5-HTP was found to increase plasma renin activity in rats". The cited article specifically says, "At the doses used, serotonin decreased mean blood pressure and colonic temperature of unanesthetized rats while ...
The amino acid 5-HTP, or 5-hydroxytryptophan, has been anecdotally reported to be a mild anaphrodisiac, as has the serotonergic empathogen MDMA, popularly known as "ecstasy". However, systematic study of these chemicals is lacking, due to the off-patent nature of 5-HTP, and the legal control of MDMA.
Additionally, some clinically used drugs such as chlorpheniramine, dextromethorphan, and methadone possess SRI properties secondarily to their primary mechanism of action(s) and this contributes to their side effect and drug interaction profiles. A closely related type of drug is a serotonin releasing agent (SRA), an example of which is ...
The good news is that some common scams are easy to spot. The bad news is that some are technologically improving faster than you or even law enforcement can track.
The good news is that scams operate in many known area codes, so you can avoid being the next victim simply by honing in on the list of scammer phone numbers. Read Next: 6 Unusual Ways To Make ...
Scam artists remind us that we made this all up! We decided, as a society, how things should function and then created a bunch of laws to make sure things keep functioning that way. And when I say ...
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