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High-grade serous carcinoma (HGSC) is a type of tumour that arises from the serous epithelial layer in the abdominopelvic cavity and is mainly found in the ovary. HGSCs make up the majority of ovarian cancer cases [ 1 ] and have the lowest survival rates. [ 2 ]
Unsurprisingly, 5-year survival decreases as the stage increases. There is a 25% survival rate with a stage III serous carcinoma. Staging: Stage I - Tumour growth limited to ovaries. Stage II - Growth involving one or both ovaries with pelvic extension.
The most common cancer among women in the United States is breast cancer (123.7 per 100,000), followed by lung cancer (51.5 per 100,000) and colorectal cancer (33.6 per 100,000), but lung cancer surpasses breast cancer as the leading cause of cancer death among women. [13]
Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas. [1] Symptoms include enlarged lymph nodes, fever, night sweats, weight loss, and tiredness. [1] Other symptoms may include bone pain, chest pain, or itchiness. [1]
Bone cancer (including joint cancer) 0.5 Skin cancer (excluding basal and squamous) 3.4 Breast cancer (non-in situ) 11.3 Uterine cancer (cervix uteri) 1.2 Uterine cancer (corpus uteri) 1.2 Uterine cancer (not otherwise specified) 1.4 Ovarian cancer: 3.8 Prostate cancer: 7.8 Bladder cancer: 4.4 Renal cancer (kidney and renal pelvis cancer) 3.7 ...
The five-year survival rate for all stages of ovarian cancer is 46%; the one-year survival rate is 72% and the ten-year survival rate is 35%. [132] For cases where a diagnosis is made early in the disease, when the cancer is still confined to the primary site, the five-year survival rate is 92.7%. [133]
In the older literature survival rates have been given as 35–50% for stage I–II and 0–15% for stage III and IV uterine papillary serous carcinoma, [4] More recently it was reported that forty-two percent of 138 patients were found disease-free at five years. [3]
Papillary serous cystadenocarcinomas are the most common form of malignant ovarian cancer making up 26 percent of ovarian tumours in women aged over 20 in the United States. [ 1 ] As with most ovarian tumours, due to the lack of early signs of disease these tumours can be large when discovered and have often metastasized , often by spreading ...