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The pain is often described as stabbing or burning, or abnormal skin sensations such as tingling or itchiness. In some individuals, the pain is more severe during times of rest or at night. The signs and symptoms of small fiber neuropathy can occur at any point in life depending on the underlying cause.
Mononeuritis multiplex is sometimes associated with a deep, aching pain that worsens at night and frequently in the lower back, hip, or leg. In people with diabetes mellitus, mononeuritis multiplex typically is encountered as acute, unilateral, and severe thigh pain followed by anterior muscle weakness and loss of knee reflex.
Whilst these common symptoms are usually present in many patients with NC, rarer and more serious symptoms can occur in severe cases of NC. In extreme cases of NC constant discomfort, pain or numbness is experienced. This results in patients to have decreased mobility and function as excessive or constant movements cause pain.
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Motor symptoms can usually be aided through "mechanical aids" such as hand or foot braces, orthopaedic shoes, splints, and in more severe cases procedures such as tendon transfers or bone fusions can take place. [4] All of these aids and procedures can reduce physical disability, pain, pressured or compressed nerves and weaknesses. [4]
The symptoms affect just one particular part of the body, depending on which nerve is affected. The diagnosis is largely clinical and can be confirmed with diagnostic nerve blocks. Occasionally imaging and electrophysiology studies aid in the diagnosis. Timely diagnosis is important as untreated chronic nerve compression may cause permanent damage.
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