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The aims of EULAR are to reduce the burden of rheumatic diseases on the individual and society and to improve the treatment, prevention and rehabilitation of musculoskeletal diseases. It promotes the translation of research advances into daily care and fights for the recognition of the needs of people with musculoskeletal diseases by the ...
Neuropsychiatric systemic lupus erythematosus or NPSLE refers to the neurological and psychiatric manifestations of systemic lupus erythematosus.SLE is a disease in which the immune system attacks the body's own cells and tissues.
SLE is one of several diseases known as "the great imitator" because it often mimics or is mistaken for other illnesses. [12] SLE is a classical item in differential diagnosis, [13] because SLE symptoms vary widely and come and go unpredictably. Diagnosis can thus be elusive, with some people having unexplained symptoms of SLE for years before ...
Sifalimumab is a human monoclonal antibody designed for the treatment of SLE, dermatomyositis, and polymyositis. [1] It targets interferon a. [2] Sifalimumab was developed by MedImmune; as of 2017 development had been terminated in favor of moving a competing internal product, anifrolumab, into Phase III trials. [3] [4] [5]
Epratuzumab binds to the glycoprotein CD22 of mature and malignant B-cells.. Elevated CD22 and other B-cell receptor (BCR) proteins are associated with SLE. "Epratuzumab's mechanism of action transfers these BCR proteins to helper cells called effector cells which reduces B-cell destruction and epratuzumab's impact on the body's immune system" [6] via a process called trogocytosis. [3]
Lupus nephritis is an inflammation of the kidneys caused by systemic lupus erythematosus (SLE) and childhood-onset systemic lupus erythematosus which is a more severe form of SLE that develops in children up to 18 years old; both are autoimmune diseases. [3] [4] It is a type of glomerulonephritis in which the glomeruli become inflamed.
Below is a list of the films that have been submitted by Nepal for review by the Academy for the award by year and the respective Academy Awards ceremony. Caravan was filmed in Dolpali language much similar to the Tibetan, while Basain , Mask of Desire and Muna Madan were filmed in Nepali .
The following is a list of highest-grossing films in Nepal, with gross revenue in Nepali Rupees.The prominent films released in Nepal before 2075 BS (2018 CE) had no official tracking of figures and thus contains generally accepted figures provided by producers, distributors and media reports.
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related to: eular sle guidelines 2023 pdf nepal printable 2024 form w 2 box 12 code dd