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Post-exertional malaise (PEM), sometimes referred to as post-exertional symptom exacerbation (PESE) [1] or post-exertional neuroimmune exhaustion (PENE), [2] is a worsening of symptoms that occurs after minimal exertion. It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and ...
As a result of this effect, not only is the soreness reduced the next time the exercise is performed, but other indicators of muscle damage, such as swelling, reduced strength, and reduced range of motion, are also more quickly recovered from.
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Post-exertional malaise (PEM) and exercise intolerance are common symptoms of post-acute infection syndromes. [5] Post-exertional malaise is a worsening of symptoms after minimal physical or mental activity, [ 6 ] and is a cardinal symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). [ 7 ]
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Muscle fatigue is when muscles that were initially generating a normal amount of force, then experience a declining ability to generate force. It can be a result of vigorous exercise , but abnormal fatigue may be caused by barriers to or interference with the different stages of muscle contraction .
If the next workout takes place during the recovery period, overtraining may occur. If the next workout takes place during the supercompensation period, the body will advance to a higher level of fitness. If the next workout takes place after the supercompensation period, the body will remain at its base level.
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