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Confocal microscopy is the microscopic procedure of choice for examining neuron structures as it produces sharp images with improved resolution and decreased signal-to-noise ratio. The specific way this microscopy works allows one to look at one confocal plane at a time, which is optimal when viewing neuronal structures.
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Digital reconstruction or tracing of neuron morphology is a fundamental task in computational neuroscience. [1] [2] [3] It is also critical for mapping neuronal circuits based on advanced microscope images, usually based on light microscopy (e.g. laser scanning microscopy, bright field imaging) or electron microscopy or other methods. Due to ...
Images (3D, 4D) Various No Neuroelectro.org Electrophysiology of neurons Human, others Neuron Electrophysiological properties and data Healthy No [33] Neuromorpho.org 3D models of real neurons Human, rat, mouse, monkey, others Neuron Images and 3D data Healthy No [34] Neuromorphometrics.com: Manually labeled MRI Brain Scans Human Macroscopic
A reconstruction of a pyramidal cell. Soma and dendrites are labeled in red, axon arbor in blue. (1) Soma, (2) Basal dendrite, (3) Apical dendrite, (4) Axon, (5) Collateral axon. One of the main structural features of the pyramidal neuron is the conic shaped soma, or cell body, after which the neuron is named.
The soma of a neuron (i.e., the main part of the neuron in which the dendrites branch off of) contains many organelles, including granules called Nissl granules, which are composed largely of rough endoplasmic reticulum and free polyribosomes. [5] The cell nucleus is a key feature of the soma.
Glial stem cells are found in all parts of the adult brain. [1] Glial cells greatly outnumber neurons and apart from their supporting role to neurons, glia – astrocytes in particular have been acknowledged as being able to communicate with neurons involving a signalling process similar to neurotransmission called gliotransmission. [4]
Like all animal cells, the cell body of every neuron is enclosed by a plasma membrane, a bilayer of lipid molecules with many types of protein structures embedded in it. [12] A lipid bilayer is a powerful electrical insulator , but in neurons, many of the protein structures embedded in the membrane are electrically active.
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