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Cancer Discovery publishes high-impact articles featuring major advances in research and clinical trials. Topics span the spectrum of cancer research and medicine from the laboratory to the clinic to epidemiologic studies.
Blood Cancer Discovery; Cancer Discovery; Cancer Epidemiology, Biomarkers & Prevention; Cancer Immunology Research; Cancer Prevention Research; Cancer Research; Cancer Research Communications; Clinical Cancer Research; Molecular Cancer Research; Molecular Cancer Therapeutics
Cancer Discovery publishes high-impact, peer-reviewed articles describing major advances in research and clinical trials. As the premier cancer information resource, the Journal also presents Review Articles, Perspectives and Commentaries, News stories, and Research Watch summaries of important journal articles to its readers to keep them ...
View article titled, Early Detection of Ovarian Cancer Using Cell-Free DNA Fragmentomes and Protein Biomarkers
Overall, this study unifies targeted therapy and immunotherapy and suggests that targetable neoantigens may enhance therapeutic effectiveness against cancer. For more information, see the article by Hattori, Maso, and colleagues on page 132
The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity of cancer phenotypes and genotypes into a provisional set of underlying principles. As knowledge of cancer mechanisms has progressed, other facets of the disease have emerged as potential refinements.
The Hallmarks of Cancer provides a set of underlying principles to explain the mechanisms of malignant tumor formation and cancer progression. Originally including six hallmarks, the framework was later expanded to encompass four new features.
Eflornithine Improves Survival in Brain Cancer Treatment with eflornithine led to clinically meaningful improvements in overall survival (OS) and progression-free survival (PFS) for patients with recurrent grade 3 IDH -mutant astrocytoma, an aggressive brain tumor composed of astrocytes.
This collection exemplifies Cancer Discovery’s commitment to connecting with Chinese researchers and showcasing their innovative efforts to drive progress in understanding cancer biology and improving outcomes for patients worldwide.
These data highlight a central role for cancer cell-intrinsic IRF3/type-I IFN production in deferiprone-induced NK cell accumulation at metastatic ovarian cancer sites. How does type-I IFN induced by deferiprone support antitumor NK cell responses?