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The liver parenchyma is the functional tissue of the organ made up of around 80% of the liver volume as hepatocytes. The other main type of liver cells are non-parenchymal. Non-parenchymal cells constitute 40% of the total number of liver cells but only 6.5% of its volume. [11]
[44] [32] Cirrhosis caused by hepatitis C and alcoholic liver disease are the most common reasons for liver transplant. [32] Both hepatitis C and hepatitis B–related cirrhosis can also be attributed with heroin addiction. [54] Chronic hepatitis B causes liver inflammation and injury that over several decades can lead to cirrhosis. [44]
Chronic liver disease in the clinical context is a disease process of the liver that involves a process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis. [1] "Chronic liver disease" refers to disease of the liver which lasts over a period of six months.
Portal vein thrombosis causes upper abdominal pain, possibly accompanied by nausea and an enlarged liver and/or spleen; the abdomen may be filled with fluid (). [3]A persistent fever may result from the generalized inflammation. [1]
At birth, the liver comprises roughly 4% of body weight and weighs on average about 120 g (4 oz). Over the course of further development, it will increase to 1.4–1.6 kg (3.1–3.5 lb) but will only take up 2.5–3.5% of body weight. [40] Hepatosomatic index (HSI) is the ratio of liver weight to body weight. [41]
They have a direct toxic effect on the liver; cause inflammation of liver caused by and thereby impact lipid metabolism and fatty liver disease; and can translocate from the lungs to the liver. [46] Because particulate matter and carbon black are very diverse and each has different toxicodynamics, detailed mechanisms of translocation are not clear.
The development of infection in definitive host is divided into two phases: the parenchymal (migratory) phase and the biliary phase. [16] The parenchymal phase begins when excysted juvenile flukes penetrate the intestinal wall. After the penetration of the intestine, flukes migrate within the abdominal cavity and penetrate the liver or other ...
Severe abdominal pain is the predominant symptom. A person can puncture their spleen if they crack their rib. Because there is a strong flow of blood in the spleen, there is a higher chance of excessive bleeding. Cirrhosis is a complication of many liver diseases characterized by abnormal structure and function of the liver. The diseases that ...