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The Stillman diet is a high-protein, low-carbohydrate diet devised in 1967 by physician Irwin Maxwell Stillman (1896–1975). [1] It focusses mostly on the complete avoidance of both fats and carbohydrates, and requires at least eight glasses of water to be consumed every day.
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The Prescribing Information follows one of two formats: "physician labeling rule" format or "old" (non-PLR) format. For "old" format labeling a "product title" may be listed first and may include the proprietary name (if any), the nonproprietary name, dosage form(s), and other information about the product. The other sections are as follows:
Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.
There is limited evidence that low-fat diets compared to high-fat diets, decreased men's total and free testosterone levels. [8] The decrease in testosterone on low-fat diets is thought to be due to a decrease in testicular testosterone synthesis, since both urinary testosterone and dihydrotestosterone also decrease on low-fat diets. [8]
The routine use of VLCDs is not recommended due to safety concerns, but this approach can be used under medical supervision if there is a clinical rationale for rapid weight loss in obese individuals, as part of a "multi-component weight management strategy" with continuous support and for a maximum of 12 weeks, according to the NICE 2014 guidelines. [12]