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Equine estrogens, or horse estrogens ... Binding affinities were determined via displacement studies in a variety of in-vitro systems with labeled estradiol and ...
Unlike people, horses usually tolerate the procedure well, with little pain. This sample is cultured by a lab over the course of a few weeks before being shipped back to the horse, and then injected into the site of injury. Adipose-derived MSC are harvested from fat from the abdomen, chest, or tail head. Unlike bone marrow-derived cells ...
Conjugated estrogens (CEs), or conjugated equine estrogens (CEEs), sold under the brand name Premarin among others, is an estrogen medication which is used in menopausal hormone therapy and for various other indications.
Estradiol has been used at high doses to suppress sex drive in men with sexual deviance such as paraphilias and in sex offenders. [84] [85] [86] It has specifically been used for this indication in the forms of intramuscular injections of estradiol valerate and estradiol undecylate and of subcutaneous pellet implants of estradiol. [84] [85] [86]
Estrone in oil solution by intramuscular injection is rapidly absorbed, while estrone in aqueous suspension has a prolonged period of absorption. [62] Upon intramuscular injection of estrone in aqueous solution, the water from the preparation is absorbed and a microcrystalline depot of estrone that is slowly absorbed by the body is formed. [37]
Tritiated estradiol radioactivity in blood with a single intramuscular injection of 1.5 to 2.8 μg tritiated estradiol in aqueous solution in four women. [1] Peak blood radioactivity occurred within 15 minutes in three of the women and in the remaining woman after 2 hours. [1] Source: Davis et al. (1963). [1]
Synthetic estradiol, taken orally, decomposes when absorbed in the gastrointestinal tract and delivers bioidentical estradiol to the bloodstream. [23] The hormone estriol, produced during pregnancy, is frequently compounded into bioidentical preparations in the United States.
Estradiol is an estrogen, or an agonist of the nuclear estrogen receptors (ERs), the estrogen receptor alpha (ERα) and the estrogen receptor beta (ERβ). [1] [2] [6] In one study, the EC 50 Tooltip half-maximal effective concentration value of estradiol for the human ERα was 50 pM (0.05 nM) and for the human ERβ was 200 pM (0.2 nM).