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People with high triglyceride levels may be candidates for icosapent ethyl (Vascepa), a drug made from highly purified fish oil. It lowers triglycerides and, when taken with a statin, lowers the risk of heart attack, stroke, and death from cardiac causes.
Fortunately, you can lower triglyceride levels naturally with dietary, exercise, and lifestyle changes—plus prescription medication, if necessary.
Lowering carbohydrate intake (especially refined carbohydrates) and increasing fat (especially omega-3 fatty acids) and protein intake can lower triglyceride levels.
Fibrate medications, such as fenofibrate (TriCor, Fenoglide, others) and gemfibrozil (Lopid), can lower your triglyceride levels. Fibrates aren't used if you have severe kidney or liver disease. Fish oil. Also known as omega-3 fatty acids, fish oil can help lower your triglycerides.
What are some of the best medications for lowering triglyceride levels? Niacin. Fibrates. Icosapent ethyl. Volanesorsen. Gene therapy. Underlying conditions. Lifestyle changes....
How to Lower Triglycerides With Medications. Lifestyle changes are often the best approach to lowering triglycerides. But some people need medication as well.
But sometimes diet and exercise aren't enough. You might also need to take cholesterol medications to help: Decrease your low-density lipoprotein (LDL) cholesterol, the "bad" cholesterol that increases the risk of heart disease. Decrease your triglycerides, a type of fat in the blood that also increases the risk of heart disease.