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Concerns over the high incidence of reported side effects with ketorolac led to its withdrawal (apart from the ophthalmic formulation) in several countries, while in others its permitted dosage and maximum duration of treatment have been reduced. From 1990 to 1993, 97 reactions with fatal outcomes were reported worldwide. [37]
A medication overuse headache (MOH), also known as a rebound headache, usually occurs when painkillers are taken frequently to relieve headaches. [1] These cases are often referred to as painkiller headaches. [2] Rebound headaches frequently occur daily, can be very painful and are a common cause of chronic daily headache.
Hypertriglyceridaemia (elevated blood triglycerides) Hypercholesterolaemia (elevated blood cholesterol levels) Hyperglycaemia (elevated blood glucose levels). This may be the result of olanzapine's inhibitory effects on the M 3 receptor which regulates the release of insulin from the pancreas. [2] Brain shrinkage (dose dependent) [4] [5] [6] [7]
Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. [1] Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion and occasionally loss of consciousness. [1]
Protein toxicity is the effect of the buildup of protein metabolic waste compounds, like urea, uric acid, ammonia, and creatinine.Protein toxicity has many causes, including urea cycle disorders, genetic mutations, excessive protein intake, and insufficient kidney function, such as chronic kidney disease and acute kidney injury.
Creatinine itself is produced [5] via a biological system involving creatine, phosphocreatine (also known as creatine phosphate), and adenosine triphosphate (ATP, the body's immediate energy supply). Creatine is synthesized primarily in the liver by methylation of glycocyamine (guanidino acetate, synthesized in the kidney from the amino acids ...
Overall, side effects from a half-strength third dose of Moderna's vaccine were similar to a second dose. Younger people recorded more side effects. Overall, side effects from a half-strength ...
Chronic headaches consist of different sub-groups, primarily categorized as chronic tension-type headaches and chronic migraine headaches. [2] The treatments for chronic headache are vast and varied. Medicinal and non-medicinal methods exist to help patients cope with chronic headache, because chronic headaches cannot be cured. [ 3 ]
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