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  2. Succinic acid - Wikipedia

    en.wikipedia.org/wiki/Succinic_acid

    Succinic acid (/ s ə k ˈ s ɪ n ɪ k /) is a dicarboxylic acid with the chemical formula (CH 2) 2 (CO 2 H) 2. [5] In living organisms, succinic acid takes the form of an anion, succinate, which has multiple biological roles as a metabolic intermediate being converted into fumarate by the enzyme succinate dehydrogenase in complex 2 of the electron transport chain which is involved in making ...

  3. Succimer - Wikipedia

    en.wikipedia.org/wiki/Succimer

    Succimer is an isomer of 2,3-dimercaptosuccinic acid. 2,3-dimercaptosuccinic acid is the organosulfur compound with the formula HO 2 CCH(SH)CH(SH)CO 2 H. This colorless solid contains two carboxylic acid and two thiol groups, the latter being responsible for its mildly unpleasant odour.

  4. Succinimide - Wikipedia

    en.wikipedia.org/wiki/Succinimide

    Several succinimides are used as anticonvulsant drugs, including ethosuximide, phensuximide, and methsuximide. [ 5 ] Succinimides are also used to form covalent bonds between proteins or peptides and plastics, which is useful in a variety of assay techniques.

  5. Dibasic ester - Wikipedia

    en.wikipedia.org/wiki/Dibasic_ester

    Dibasic ester or DBE is an ester of a dicarboxylic acid.Depending on the application, the alcohol may be methanol or higher molecular weight monoalcohols. Mixtures of different methyl dibasic esters are commercially produced from short-chain acids such as adipic acid, glutaric acid, and succinic acid. [1]

  6. Merck pursuing next-generation opportunities in ... - AOL

    www.aol.com/news/merck-pursuing-next-generation...

    By Mariam Sunny and Sneha S K (Reuters) -Merck is focused on second- and third-generation opportunities in the cardiometabolic drugs market, which includes weight-loss treatments, the company said ...

  7. FDA panel flags insufficient data for Merck's chronic cough drug

    www.aol.com/news/us-fda-panel-votes-against...

    The U.S. Food and Drug Administration's (FDA) panel voted 12 to 1 against the late-stage data submitted by Merck for the drug gefapixant, which showed a small reduction in cough frequency compared ...

  8. Discovery and development of ACE inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    L-benzyl succinic acid (2(R)-benzyl-3-carboxypropionic acid) was described to be the most potent inhibitor of carboxypeptidase A in the early 1980s. The authors referred to it as a by-product analog and it was proposed to bind to the active site of carboxypeptidase A via succinyl carboxyl group and a carbonyl group. Their findings established ...

  9. Succinyl chloride - Wikipedia

    en.wikipedia.org/wiki/Succinyl_chloride

    It is the acyl chloride derivative of succinic acid and a simple diacid chloride. It is a colorless liquid. It is a colorless liquid. It used as a reagent in organic synthesis .

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