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Clindamycin. Clindamycin is a lincosamide antibiotic medication used for the treatment of a number of bacterial infections, including osteomyelitis (bone) or joint infections, pelvic inflammatory disease, strep throat, pneumonia, acute otitis media (middle ear infections), and endocarditis. [5] It can also be used to treat acne, [5][6] and some ...
29,000 (US) [2][4] Clostridioides difficile infection[5] (CDI or C-diff), also known as Clostridium difficile infection, is a symptomatic infection due to the spore -forming bacterium Clostridioides difficile. [6] Symptoms include watery diarrhea, fever, nausea, and abdominal pain. [1] It makes up about 20% of cases of antibiotic-associated ...
Clostridioides difficile (syn. Clostridium difficile) is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. [ 4 ][ 5 ] It is known also as C. difficile, or C. diff (/ siːdɪf /), and is a Gram-positive species of spore -forming bacteria. [ 6 ]Clostridioides spp. are anaerobic, motile bacteria ...
Lincosamides can interact with anesthetic agents to produce neuromuscular effects. [29] Other adverse reactions include diarrhea, nausea, vomiting, abdominal pain and rash. Topical administration of clindamycin may induce contact dermatitis, dryness, burning, itching, scaliness and peeling of the skin.
Antibiotic-associated diarrhea (AAD) results from an imbalance in the colonic microbiota caused by antibiotics. Microbiotal alteration changes carbohydrate metabolism with decreased short-chain fatty acid absorption and an osmotic diarrhea as a result. Another consequence of antibiotic therapy leading to diarrhea is an overgrowth of potentially ...
Clostridioides difficile colitis may occur in connection with the use of any antibacterial drug, especially those with a broad spectrum of activity such as clindamycin, cephalosporins, and fluoroquinolones. Fluoroquinoline treatment is associated with risk that is similar to [30] or less than [31] [32] that associated with broad spectrum ...
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