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Game designer Cliff Johnson defines a meta-puzzle as "a collection of puzzles that, when solved, each give a piece of a master puzzle." [2] A metapuzzle is a puzzle that unites several puzzles that feed into it. For example, five puzzles that had the answers BLACK, HAMMER, FROST, KNIFE, and UNION would lead to the metapuzzle answer JACK, which ...
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Crossword-like puzzles, for example Double Diamond Puzzles, appeared in the magazine St. Nicholas, published since 1873. [32] Another crossword puzzle appeared on September 14, 1890, in the Italian magazine Il Secolo Illustrato della Domenica. It was designed by Giuseppe Airoldi and titled "Per passare il tempo" ("To pass the time"). Airoldi's ...
Prof. David Baker, a protein research scientist at the University of Washington, founded the Foldit project.Seth Cooper was the lead game designer. Before starting the project, Baker and his laboratory coworkers relied on another research project named Rosetta [5] to predict the native structures of various proteins using special computer protein structure prediction algorithms.
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In 1981, the code base split into GAMESS (US) and GAMESS (UK) variants, which now differ significantly. GAMESS (US) is maintained by the members of the Gordon Research Group at Iowa State University. [7] GAMESS (US) source code is available as source-available freeware, but is not open-source software, due to license restrictions.
Regional anatomy is the study of the interrelationships of all of the structures in a specific body region, such as the abdomen. In contrast, systemic anatomy is the study of the structures that make up a discrete body system—that is, a group of structures that work together to perform a unique body function, such as the digestive system. [10]
Neoplasia is the medical term used for both benign and malignant tumors, or any abnormal, excessive, uncoordinated, and autonomous cellular or tissue growth. Desmoplastic reaction to breast cancer. Desmoplasia refers to growth of dense connective tissue or stroma. [2]