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  2. Ventilation–perfusion coupling - Wikipedia

    en.wikipedia.org/wiki/Ventilation–perfusion...

    Smoking (long-term exposure to chemical irritants) can cause COPD, increasing the risk of lung cancer and heart disease. [14] Asthma is a common inflammatory disease causing the airway to swell and disturb breathing and ventilation(low V/A ratio). The cause is unrevealed, but allergens such as pollen, mold, respiratory infections, and air ...

  3. Pathophysiology of asthma - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_asthma

    During an asthma episode, inflamed airways react to environmental triggers such as smoke, dust, or pollen. The airways narrow and produce excess mucus, making it difficult to breathe. In essence, asthma is the result of an immune response in the bronchial airways. [3]

  4. Transpulmonary pressure - Wikipedia

    en.wikipedia.org/wiki/Transpulmonary_pressure

    The alveolar pressure is estimated by measuring the pressure in the airways while holding one's breath. [2] The intrapleural pressure is estimated by measuring the pressure inside a balloon placed in the esophagus. [2] Measurement of transpulmonary pressure assists in spirometry in availing for calculation of static lung compliance.

  5. Asthma - Wikipedia

    en.wikipedia.org/wiki/Asthma

    Low blood pressure "Normal" PaCO 2: Cyanosis: Silent chest Poor respiratory effort Acute severe (any one of) Peak flow 33–50% Respiratory rate ≥ 25 breaths per minute Heart rate ≥ 110 beats per minute Unable to complete sentences in one breath Moderate Worsening symptoms Peak flow 50–80% best or predicted No features of acute severe asthma

  6. Dynamic hyperinflation - Wikipedia

    en.wikipedia.org/wiki/Dynamic_hyperinflation

    Dynamic hyperinflation is a phenomenon that occurs when a new breath begins before the lung has reached the static equilibrium volume. [1] In simpler terms, this means that a new breath starts before the usual amount of air has been breathed out, leading to a build-up of air in the lungs, and causing breathing in and out to take place when the lung is nearly full.

  7. Peak expiratory flow - Wikipedia

    en.wikipedia.org/wiki/Peak_expiratory_flow

    50 to 79 percent of the usual or normal peak flow readings Indicates caution. It may mean respiratory airways are narrowing and additional medication may be required. Red Zone Less than 50 percent of the usual or normal peak flow readings Indicates a medical emergency. Severe airway narrowing may be occurring and immediate action needs to be ...

  8. Work of breathing - Wikipedia

    en.wikipedia.org/wiki/Work_of_breathing

    The normal relaxed state of the lung and chest is partially empty. Further exhalation requires muscular work. Inhalation is an active process requiring work. [4] Some of this work is to overcome frictional resistance to flow, and part is used to deform elastic tissues, and is stored as potential energy, which is recovered during the passive process of exhalation, Tidal breathing is breathing ...

  9. Bronchoconstriction - Wikipedia

    en.wikipedia.org/wiki/Bronchoconstriction

    The most common cause of emphysema is smoking and smoking cessation is mandatory if this incurable disease is to be treated. Prevention of bronchoconstriction by this pathway is vital for people with emphysema and there are several anticholinergic medications that in combination with mucous thinning agents such as Guaifenesin cause significant ...

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