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Topical drug delivery (TDD) is a route of drug administration that allows the topical formulation to be delivered across the skin upon application, hence producing a localized effect to treat skin disorders like eczema. [1] [2] The formulation of topical drugs can be classified into corticosteroids, antibiotics, antiseptics, and anti-fungal.
Topical drug delivery is a route of administering drugs via the skin to provide topical therapeutic effects. As skin is one of the largest and most superficial organs in the human body, pharmacists utilise it to deliver various drugs. This system usually provides a local effect on certain positions of the body.
Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [3] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
Routes can also be classified based on where the target of action is. Action may be topical (local), enteral (system-wide effect, but delivered through the gastrointestinal tract), or parenteral (systemic action, but is delivered by routes other than the GI tract). Route of administration and dosage form are aspects of drug delivery.
Modern drug delivery solutions, including controlled release and targeted delivery systems, are enabling better disease management by providing precise dosages and reducing side effects. Self-administration technologies, such as wearable injectors and auto-injectors, empower patients to take control of their treatment regimens in the comfort of ...
For transdermal delivery, drugs must pass through the two sublayers of the epidermis to reach the microcirculation of the dermis. The stratum corneum is the top layer of the skin and varies in thickness from approximately ten to several hundred micrometres, depending on the region of the body. [1]
Shares of drug delivery systems manufacturer Unilife recently rallied after it announced a long-term contract to sell prefilled syringes to pharma giant Sanofi . The deal allows Sanofi to sell its ...
Originally created to treat ulcers (it didn’t work for that), scientists realized the drug dilated blood vessels. In 1979 , minoxidil tablets were FDA-approved as a treatment for high blood ...
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