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The neuroscience of sleep is the study of the neuroscientific and physiological basis of the nature of sleep and its functions. Traditionally, sleep has been studied as part of psychology and medicine. [1] The study of sleep from a neuroscience perspective grew to prominence with advances in technology and the proliferation of neuroscience ...
Sleep cycle. The sleep cycle is an oscillation between the slow-wave and REM (paradoxical) phases of sleep. It is sometimes called the ultradian sleep cycle, sleep–dream cycle, or REM-NREM cycle, to distinguish it from the circadian alternation between sleep and wakefulness. In humans, this cycle takes 70 to 110 minutes (90 ± 20 minutes). [1]
Polysomnographic record of REM Sleep. EEG highlighted by red box. Eye movement highlighted by red line. REM sleep is called "paradoxical" because of its similarities to wakefulness. Although the body is paralyzed, the brain acts as if it is somewhat awake, with cerebral neurons firing with the same overall intensity as in wakefulness.
Sleep stages are characterized by spectral content of EEG: for instance, stage N1 refers to the transition of the brain from alpha waves (common in the awake state) to theta waves, whereas stage N3 (deep or slow-wave sleep) is characterized by the presence of delta waves. [107] The normal order of sleep stages is N1 → N2 → N3 → N2 → REM.
Polysomnography (PSG) is a multi-parameter type of sleep study [1] and a diagnostic tool in sleep medicine.The test result is called a polysomnogram, also abbreviated PSG.The name is derived from Greek and Latin roots: the Greek πολύς (polus for "many, much", indicating many channels), the Latin somnus ("sleep"), and the Greek γράφειν (graphein, "to write").
Hypnagogia is the transitional state from wakefulness to sleep, also defined as the waning state of consciousness during the onset of sleep. Its opposite state is described as hypnopompia – the transitional state from sleep into wakefulness. Mental phenomena that may occur during this "threshold consciousness" phase include hypnagogic ...
Sleep spindlesare bursts of neural oscillatory activitythat are generated by interplay of the thalamic reticular nucleus(TRN) and other thalamicnuclei during stage 2 NREM sleepin a frequency range of ~11 to 16 Hz (usually 12–14 Hz) with a duration of 0.5 seconds or greater (usually 0.5–1.5 seconds). [1][2][3]After generation as an ...
Hippocampus. The hippocampus (pl.: hippocampi; via Latin from Greek ἱππόκαμπος, ' seahorse ') is a major component of the brain of humans and other vertebrates. Humans and other mammals have two hippocampi, one in each side of the brain. The hippocampus is part of the limbic system, and plays important roles in the consolidation of ...