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When multiple EPSPs occur on a single patch of postsynaptic membrane, their combined effect is the sum of the individual EPSPs. Larger EPSPs result in greater membrane depolarization and thus increase the likelihood that the postsynaptic cell reaches the threshold for firing an action potential.
In premature babies, the incidence and mortality rates are higher due to the weakness of their immune system. For infants with low birth weight, cases of early-onset sepsis is found to be about 26 per 1,000 and 8 per 1,000 live births. Certain populations of babies are at more risk as well.
Most cases occur due to inadequate antenatal screening and treatment during pregnancy. [8] The baby is highly infectious if the rash and snuffles are present. [4] The disease may be suspected from tests on the mother; blood tests and ultrasound. [9] Tests on the baby may include blood tests, CSF analysis and medical imaging. [10]
The mother's antibodies can remain in the baby's bloodstream for weeks, and bleeding can occur in the baby before birth (fetal), during birth or after birth (neonatal). [ 9 ] A number of different proteins can cause NAIT, about 80% of cases are caused by antibodies against platelet antigen HPA -1a , 15% by anti- HPA -5b , and 5% by other ...
EPSP synthase is a monomeric enzyme with a molecular mass of approximately 46,000. [2] [3] [4] It consists of two domains connected by protein strands that function as a hinge, allowing the two domains to move closer together.
Sheehan's syndrome typically occurs because of excessive blood loss after delivery (post-partum hemorrhage), although there are several risk factors that may contribute to its development. [9] This syndrome does not appear to be exclusively linked to childbirth, as Sheehan's syndrome has been reported in pregnant patients that experienced ...
Hypoxia refers to deficiency of oxygen, Ischemia refers to restriction in blood flow to the brain. The result is “encephalopathy” which refers to damaged brain cells. Encephalopathy is a nonspecific response of the brain to injury which may occur via multiple methods, but is commonly caused by birth asphyxia, leading to cerebral hypoxia. [2 ...
As these are the various points to which insults can occur to the foetus. [citation needed] Antepartum causes. Inadequate oxygenation of maternal blood due to hypoventilation during anesthesia, heart diseases, pneumonia, respiratory failure; Low maternal blood pressure due to hypotension e.g. compression of vena cava and aorta, excess anaesthesia.