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Saw palmetto extract should not be used during pregnancy because it may affect androgen and estrogen metabolism. [3] [7] As there is no rationale for using saw palmetto during pregnancy, it should be avoided when pregnant or while breastfeeding. [3]
To answer your question (okay, fine, our question), saw palmetto does block DHT — at least in part. The harder thing to answer is to what extent it blocks the hormone. The harder thing to answer ...
Additionally, it has been claimed that alfatradiol works through this mechanism of activity (5α-reductase), as well as the Ganoderic acids in lingzhi mushroom, and the Saw Palmetto. Inhibition of 5α-reductase results in decreased conversion of testosterone to DHT, leading to increased testosterone and estradiol.
5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss.
By blocking DHT production directly at the source, finasteride drastically reduces the levels of DHT in your body. Research shows that it can lower the amount of DHT by as much as 70 percent.
Ingredients like saw palmetto, found in supplements and topicals, can block DHT as well. GRO Hair Serum. amazon.com. $48.00 at amazon.com. 3. Prioritize your scalp health.
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