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Ruxolitinib (sold under the brand names Jakafi and Jakavi among others, and as Opzelura in cream form) is a medication used for the treatment of intermediate or high-risk myelofibrosis, [6] a type of myeloproliferative neoplasm that affects the bone marrow; [11] [12] polycythemia vera, when there has been an inadequate response to or intolerance of hydroxyurea; [6] [13] and steroid-refractory ...
The prescribing information for Jakafi now includes a new recommended starting dose of 5 mg twice daily of Jakafi for patients with baseline platelet counts between 50-100 x 10 9 /L (50,000 to ...
The most common final control element in the process control industries is the control valve. The control valve manipulates a flowing fluid, such as gas, steam, water, or chemical compounds, to compensate for the load disturbance and keep the regulated process variable as close as possible to the desired set point. [1]
Simple hydraulic control valves are binary, they are either on or off. Servo valves are different in that they can continuously vary the flow they supply from zero up to their rated maximum flow, or until the output pressure reaches the supplied pressure. More complex servo valves can control other parameters.
The Lanciafiamme Spalleggiato Modello 35, also known as the Model 35, was a flamethrower issued to the Royal Italian Army in the Second Italo-Ethiopian War. In 1940 it was replaced by the Lanciafiamme Spalleggiato Modello 40 , [ a ] which used a different ignition system.
The Pup was developed to appear in 1935 as the Porterfield Model 35 Flyabout a braced high-wing-monoplane. It had a fixed tailskid landing gear and room for two. It was originally powered by a 60 hp (45 kW) LeBlond 5D radial engine. Variants later appeared with different engine installations and a deluxe model the De Luxe Sport. Over 240 ...
The Electro 35 GT was released in 1969 with a body painted black instead of the satin chrome finish. The Electro 35 GS and GT were introduced in 1970 . They (and all later Electro 35 models) have all internal electrical contacts gold plated to prevent oxidation from impeding the flow of electricity around the circuits.
A level control valve or altitude control valve is a type of valve that automatically responds to changes in the height of a liquid in some storage system. A common example is the set of ballcocks in a flush toilet , where each stage of the flush cycle is actuated by the emptying or filling of the tank.