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Hippocampal sclerosis. Hippocampal sclerosis (HS) or mesial temporal sclerosis (MTS) is a neuropathological condition with severe neuronal cell loss and gliosis in the hippocampus. [1] Neuroimaging tests such as magnetic resonance imaging (MRI) and positron emission tomography (PET) may identify individuals with hippocampal sclerosis. [2]
Nearly all reports of seizure outcome following these procedures indicate that the best outcome group includes patients with MRI evidence of mesial temporal sclerosis (hippocampal atrophy with increased T-2 signal). The range of seizure-free outcomes for these patients is reported to be between 80% and 90%, which is typically reported as a sub ...
Neurology, Psychiatry. In the field of neurology, temporal lobe epilepsy is an enduring brain disorder that causes unprovoked seizures from the temporal lobe. Temporal lobe epilepsy is the most common type of focal onset epilepsy among adults. [1] Seizure symptoms and behavior distinguish seizures arising from the medial temporal lobe from ...
Cerebral atrophy is a common feature of many of the diseases that affect the brain. [1] Atrophy of any tissue means a decrement in the size of the cell, which can be due to progressive loss of cytoplasmic proteins. In brain tissue, atrophy describes a loss of neurons and the connections between them. Brain atrophy can be classified into two ...
Frontal lobe epilepsy (FLE) is a neurological disorder that is characterized by brief, recurring seizures arising in the frontal lobes of the brain, that often occur during sleep. [1] It is the second most common type of epilepsy after temporal lobe epilepsy (TLE), and is related to the temporal form in that both forms are characterized by ...
Focal seizures (also called partial seizures[1] and localized seizures) are seizures that affect initially only one hemisphere of the brain. [2][3] The brain is divided into two hemispheres, each consisting of four lobes – the frontal, temporal, parietal and occipital lobes. A focal seizure is generated in and affects just one part of the ...
The temporal lobe is involved in primary auditory perception, such as hearing, and holds the primary auditory cortex. [6] The primary auditory cortex receives sensory information from the ears and secondary areas process the information into meaningful units such as speech and words. [6] The superior temporal gyrus includes an area (within the ...
Lee JD, Kim HJ, Lee BI, Kim OJ, Jeon TJ, Kim MJ (2000). Evaluation of ictal brain SPET using statistical parametric mapping in temporal lobe epilepsy. European Journal of Nuclear Medicine 27:1658-1665. This paper is the first use of ictal SPECT analysis by SPM for seizure localization. 4.