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Learn the definition, elements, formulas and examples of a right circular cylinder, a cylinder with perpendicular generatrices and bases. Find out how to calculate the lateral and total areas, volume and meridian section of a right circular cylinder.
Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
Body surface area (BSA) is the measured or calculated surface area of a human body. It is used in physiology and medicine for various purposes, such as dosing chemotherapy, estimating glomerular filtration rate, and calculating cardiac index.
Volume of distribution (VD) is the theoretical volume that would be necessary to contain the total amount of an administered drug at the same concentration that it is observed in the blood plasma. VD depends on the physicochemical properties of the drug and the body composition, and it affects the dose and the plasma concentration of the drug.
A cylinder is a three-dimensional solid or surface with a circular base and parallel sides. Learn about the different types of cylinders, their cylindric sections, their volume and surface area formulas, and their applications in geometry and topology.
AUC stands for area under the curve, a pharmacokinetic metric that measures the drug exposure and clearance. Learn how AUC is calculated, interpreted, and applied in different contexts, such as bioavailability, glycemic index, and PK/PD models.
The lateral surface of an object is all of the sides, excluding its base and top. The lateral surface area is the area of the lateral surface. Learn how to calculate it for different shapes such as cubes, prisms, cylinders, pyramids and cones.
The accumulation ratio of a specific drug in humans is determined by clinical studies.According to a 2013 analysis, such studies are typically done with 10 to 20 subjects who are given one single dose followed by a washout phase of seven days (), and then seven to 14 repeated doses to reach steady state conditions.