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Antibiotics by class Generic name Brand names Common uses [4] Possible side effects [4] Mechanism of action Aminoglycosides; Amikacin: Amikin: Infections caused by Gram-negative bacteria, such as Escherichia coli and Klebsiella particularly Pseudomonas aeruginosa. Effective against aerobic bacteria (not obligate/facultative anaerobes) and ...
The combination was first introduced as the name Trigesic, as the formula of 125 mg paracetamol, 230 mg aspirin, and 30 mg caffeine, in July 1950 by Squibb, which is now Bristol Myers Squibb, but was recalled in the following year due to several reports that the drug might cause blood dyscrasia. [5]
Therefore, drugs that use that enzyme, like theophylline, do not interact with levofloxacin. It is a weak inhibitor of CYP2C9, [37] suggesting potential to block the breakdown of warfarin and phenprocoumon. This can result in more action of drugs like warfarin, leading to more potential side effects, such as bleeding. [38]
Caffeine. Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class and is the most commonly consumed psychoactive substance globally. [9][10] It is mainly used for its eugeroic (wakefulness promoter), ergogenic (physical performance enhancing), or nootropic (cognition improving) properties. [11][12] Caffeine acts by ...
Propyphenazone (known as isopropylantipyrine in Japan) [1] is a derivative of phenazone [2] with similar analgesic and antipyretic effects. Originally patented in 1931, [3] propyphenazone is marketed as a combination formulation with paracetamol and caffeine for treatment of primary headache disorder. [4]
DMPX (3,7-dimethyl-1-propargylxanthine) is a caffeine analog which displays affinity to A 2 adenosine receptors, in contrast to the A 1 subtype receptors. [1] DMPX had 28× and 15× higher potency than caffeine in blocking peripheral and central NECA -responses. The locomotor stimulation caused by DMPX (ED 50 10 μ mol/kg) was similarly higher ...
Phytoestrogens are plant compounds that mimic estrogen when broken down in the body. Isoflavones are a type of phytoestrogen that comes from soybean products. This is a major category of menopause ...
Caffeic acid has a variety of potential pharmacological effects in in vitro studies and in animal models, and the inhibitory effect of caffeic acid on cancer cell proliferation by an oxidative mechanism in the human HT-1080 fibrosarcoma cell line has recently been established. [23] Caffeic acid is an antioxidant in vitro and also in vivo. [16]