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These endfeet are able to produce prostaglandin E2 (PGE2), a potent vasodilator, and 20-hydroxyeicosatetraenoic acid (20-HETE), a vasoconstrictor, both of which exert their effects on vascular smooth muscle cells in arterioles and pericytes in capillaries, leading to the vasodilation and vasoconstriction respectively.
Cerebral circulation is the movement of blood through a network of cerebral arteries and veins supplying the brain. The rate of cerebral blood flow in an adult human is typically 750 milliliters per minute, or about 15% of cardiac output. Arteries deliver oxygenated blood, glucose and other nutrients to the brain.
Microvasculature comprises the microvessels – venules and capillaries of the microcirculation, with a maximum average diameter of 0.3 millimeters. [1] As the vessels decrease in size, they increase their surface-area-to-volume ratio. This allows surface properties to play a significant role in the function of the vessel.
Anatomical terminology. [edit on Wikidata] The dural venous sinuses (also called dural sinuses, cerebral sinuses, or cranial sinuses) are venous sinuses (channels) found between the endosteal and meningeal layers of dura mater in the brain. [1][2] They receive blood from the cerebral veins, and cerebrospinal fluid (CSF) from the subarachnoid ...
Circumventricular organs (CVOs) (circum-: around ; ventricular: of ventricle) are structures in the brain characterized by their extensive and highly permeable capillaries, unlike those in the rest of the brain where there exists a blood–brain barrier (BBB) at the capillary level. [1][2][3][4] Although the term "circumventricular organs" was ...
The ependyma is the thin neuroepithelial (simple columnar ciliated epithelium) lining of the ventricular system of the brain and the central canal of the spinal cord. [1] The ependyma is one of the four types of neuroglia in the central nervous system (CNS). It is involved in the production of cerebrospinal fluid (CSF), and is shown to serve as ...
Capillaries join the arteries and veins. The circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. [1][2] It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek kardia ...
The brain is the central organ of the human nervous system, and with the spinal cord makes up the central nervous system. The brain consists of the cerebrum, the brainstem and the cerebellum. It controls most of the activities of the body, processing, integrating, and coordinating the information it receives from the sense organs, and making ...