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A bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. It is used as a cholagogue and choleretic, also industrially as a fat emulsifier. Medical Subject Headings (MeSH)
Mixtures containing water, bovine serum albumin (BSA), and sodium taurodeoxycholate (NaTDC), a component of the bile in mammals, have been investigated in a wide range of composition and pH. Depending on the concentration of both solutes and the pH, solutions.
Sodium glycodeoxycholate (NaGDC) is more effective as an absorption promoter in the nasal mucosa than sodium glycocholate (NaGC). Because of the lack of a hydroxyl group at the 7 position of the steroids, NaGDC is more lipophilic than NaGC [ 73 ].
Taurodeoxycholate (TDCA) inhibits various inflammatory responses suggesting potential clinical application. However, the toxicity of TDCA has not been evaluated in detail in vivo. We investigated the acute toxicity and 4-week repeated-dose toxicity of TDCA following intravenous infusion under Good Laboratory Practice regulations.
Sodium taurodeoxycholate is a bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. It is formed by the conjugation of ursodeoxycholic acid (UDCA) with taurine.
A bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. It is used as a cholagogue and choleretic, also industrially as a fat emulsifier.
Properties of Purified Clam CGase. Among the various detergents tested, the anionic detergent taurodeoxycholate (TDC), at a protein-to-detergent ratio of 1:1, yielded the highest activity.
Sodium taurodeoxycholate hydrate BioXtra, ≥97% (TLC); CAS Number: 207737-97-1; Synonyms: 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid,Taurodeoxycholic acid sodium salt hydrate; Linear Formula: C26H44NO6SNa · xH2O at Sigma-Aldrich
This study illustrates the application of taurodeoxycholic acid, sodium salt in chromatographic techniques, specifically enhancing the selectivity and efficiency of corticosteroid analyses, which is crucial for pharmaceutical quality control and research (Pomponio R et al., 2005).
Sodium taurodeoxycholate (TDCA) has been investigated for various inflammatory disorders such as sepsis. We recently evaluated nonclinical safety profile of TDCA using rats infused intravenously.