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Some antibiotics are not safe for people with renal failure. When prescribing certain antibiotics, doctors may adjust the dose or frequency to protect the kidneys.
Be cautious when using in patients with kidney or liver disease. Although dosage reductions are not specifically recommended, liver and kidney function should be monitored. If administered long-term, monitor liver and renal function and blood counts regularly.
Side effects that you should report to your care team as soon as possible: Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat. Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet. Rash, fever, and swollen lymph nodes.
Check with your doctor right away if you have blood in the urine, change in frequency of urination, drowsiness, increased thirst, loss of appetite, nausea or vomiting, swelling of the feet or lower legs, trouble breathing, or weakness. These may be symptoms of serious kidney problem.
Infections clindamycin treats in adults and children include serious: Infections caused by susceptible anaerobic bacteria. Infections due to susceptible isolates of streptococci, pneumococci, and staphylococci, if a less toxic alternative (such as erythromycin) is not suitable.
Most side effects of clindamycin are expected to be mild and should ease within hours to days of taking your first dose. But in rare cases, side effects may last longer. For example, kidney and...
Clindamycin is an antibiotic. It works to treat bacterial infections when penicillin is not an option. A doctor may recommend clindamycin for certain respiratory infections, lung infections,...
It has been suggested that the main pathophysiological mechanism of renal damage by clindamycin is due to direct tubular toxicity given that the onset to AKI after drug administration has been shown to be on average 1 day. 5 Proteinuria (62%) and gross hematuria (42%) can be found in clindamycin-induced AKI, and there is a possible contributing ...
We analyzed 50 patients with clindamycin-induced kidney diseases retrospectively, and investigated the characteristics of these kidney diseases in order to provide a reference for rational clinical drug use and to reduce drug-induced organ damage.
Despite its widespread use, clindamycin has been rarely associated with AKI. CASE REPORT A 52-year-old male patient with type II insulin dependent diabetes mellitus without diabetic nephropathy was treated with clindamycin for chronic osteomyelitis.