Search results
Results from the WOW.Com Content Network
Once within the bone, Ra-223 emits alpha radiation that can destroy tumor cells within a 100-micron distance. This approach has been in use since 2013 to treat prostate cancer which has metastasized to the bone. [32] Radionuclides infused into the circulation are able to reach sites that are accessible to blood vessels.
The tumor-killing capability of DaRT comes mainly from the ability of alpha radiation to irreparably break the double stranded DNA in tumor cells. [5] This capability does not seem to be dependent on the stage of the cell cycle or the level of oxygenation of the cancer cell. [citation needed]
Targeted alpha-particle therapy (or TAT) is an in-development method of targeted radionuclide therapy of various cancers. It employs radioactive substances which undergo alpha decay to treat diseased tissue at close proximity. [1] It has the potential to provide highly targeted treatment, especially to microscopic tumour cells.
One of the major limitations of radiotherapy is that the cells of solid tumors become deficient in oxygen. Solid tumors can outgrow their blood supply, causing a low-oxygen state known as hypoxia. Oxygen is a potent radiosensitizer, increasing the effectiveness of a given dose of radiation by forming DNA-damaging free radicals.
In theory BNCT is a highly selective type of radiation therapy that can target tumor cells without causing radiation damage to the adjacent normal cells and tissues. Doses up to 60–70 grays (Gy) can be delivered to the tumor cells in one or two applications compared to 6–7 weeks for conventional fractionated external beam photon irradiation.
Shielding: Sources of radiation can be shielded with solid or liquid material, which absorbs the energy of the radiation. The term 'biological shield' is used for absorbing material placed around a nuclear reactor, or other source of radiation, to reduce the radiation to a level safe for humans.
Now, the team is curious to see whether this triple complex behind Deinococcus’ antioxidant exists in cells of other organisms, and if so, if they could be responsible for radiation-resistance ...
These particles continue to decay, emitting alpha particles, which can damage cells in the lung tissue. [11] The death of Marie Curie at age 66 from aplastic anemia was probably caused by prolonged exposure to high doses of ionizing radiation, but it is not clear if this was due to alpha radiation or X-rays.