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The mean corpuscular hemoglobin concentration (MCHC) is a measure of the concentration of hemoglobin in a given volume of packed red blood cell. It is calculated by dividing the hemoglobin by the hematocrit. Reference ranges for blood tests are 32 to 36 g/dL (320 to 360g/L), [1] or between 4.81 and 5.58 mmol/L.
In microcytic anemia, the red blood cells (erythrocytes) contain less hemoglobin and are usually also hypochromic, meaning that the red blood cells appear paler than usual. This can be reflected by a low mean corpuscular hemoglobin concentration (MCHC), a measure representing the amount of hemoglobin per unit volume of fluid inside the cell ...
If the anemia is due to iron deficiency, one of the first abnormal values to be noted on a complete blood count, as the body's iron stores begin to be depleted, will be a high red blood cell distribution width, reflecting an increased variability in the size of red blood cells. [15] [23] A low mean corpuscular volume also appears during the ...
A blood smear showing hypochromic (and microcytic) anemia. Note the increased central pallor of the red blood cells. Hypochromic anemia is a generic term for any type of anemia in which the red blood cells are paler than normal. (Hypo- refers to less, and chromic means colour.) A normal red blood cell has a biconcave disk shape and will have an ...
Mean corpuscular volume (MCV) is the average volume of a red blood cell and is calculated by dividing the hematocrit (Hct) by the concentration of red blood cell count. [citation needed] = [] Normal range: 80–100 fL (femtoliter)
complete blood count [4] hemoglobin [5] serum iron [4] total iron binding capacity [4] serum ferritin [4] bone marrow examination (rarely) [4] Note: Iron therapy must be suspended 48 hours beforehand to ensure valid test results. [4] The normal range for hemoglobin is 13.8 to 17.2 grams per deciliter (g/dL) for men and 12.1 to 15.1 g/dL for ...
The mean corpuscular hemoglobin, or "mean cell hemoglobin" (MCH), is the average mass of hemoglobin (Hb) per red blood cell (RBC) in a sample of blood. It is reported as part of a standard complete blood count. MCH value is diminished in hypochromic anemias. [1] RBCs are either normochromic or hypochromic. They are never "hyperchromic".
The index is calculated from the results of a complete blood count. If the quotient of the mean corpuscular volume (MCV, in fL) divided by the red blood cell count (RBC, in million per microliter) is less than 13, β-thalassemia trait is said to be more likely. If the result is greater than 13, then iron-deficiency anemia is said to be more likely.
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