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Lymphatic filariasis is a human disease caused by parasitic worms known as filarial worms. [2] [3] Usually acquired in childhood, it is a leading cause of permanent disability worldwide, impacting over a hundred million people and manifesting itself in a variety of severe clinical pathologies [6] [7] While most cases have no symptoms, some people develop a syndrome called elephantiasis, which ...
Diethylcarbamazine is a medication used in the treatment of filariasis including lymphatic filariasis, tropical pulmonary eosinophilia, and loiasis. [1] It may also be used for prevention of loiasis in those at high risk. [1] While it has been used for onchocerciasis (river blindness), ivermectin is preferred. [2] It is taken by mouth. [3]
Mebendazole, another possible treatment for M. perstans filariasis, has been shown to be effective in significantly reducing microfilariae levels. It has been more effective than both ivermectin and DEC—with a greater number of responders, a more significant reduction in microfilariae levels, and the ability to eliminate the infection more ...
In 1998, various countries established the Global Programme to Eliminate Lymphatic Filariasis as a project of the World Health Organization. [1] This international effort had the goal of having eradication programs in every country to eliminate the disease globally.
Filariasis is a filarial infection caused by parasitic nematodes (roundworms) spread by different vectors. They are included in the list of neglected tropical diseases. The most common type is lymphatic filariasis caused by three species of Filaria that are spread by mosquitoes.
The Global Programme to Eliminate Lymphatic Filariasis (GPELF) is a World Health Organization project to eradicate the Filarioidea worms which cause the disease lymphatic filariasis and also treat the people who already have the infection.
Elephantiasis tropica (known as lymphatic filariasis), caused by a number of parasitic worms, particularly Wuchereria bancrofti. More than 120 million people, mostly in Africa and Southeast Asia, are affected. [3] Nonfilarial elephantiasis (or podoconiosis), an immune disease affecting the lymph vessels [citation needed] Leishmaniasis [2]
Where the diseases are endemic many times more are exposed routinely to infection. Some victims harbour more than one medically significant infection simultaneously and this can complicate diagnosis and treatment. [7] Humankind is the definitive host of at least eight species of filariae in various families. Six are particularly significant in ...