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This has led some researchers to suggest that other mutations may surface and make the H5N1 virus capable of human-to-human transmission. Another important factor is the change of the HA protein to a binding preference for alpha-2,6 sialic acid (the major form found in the human respiratory tract).
The Flu Virus Is Getting Savvy. ... Flu A can infect people and animals, while flu B is mostly a human virus. There are also 130 different subtype combinations of flu A, while flu B has just two ...
Dr Terrence Tumpey examines a reconstructed version of the Spanish flu virus at the CDC. An effort to recreate the Spanish flu strain (a strain of influenza A subtype H1N1) was a collaboration among the Armed Forces Institute of Pathology, the USDA ARS Southeast Poultry Research Laboratory, and Mount Sinai School of Medicine in New York
These segments act like mini-chromosomes, and each time a flu virus is assembled, it requires one copy of each segment. If a single host (a human, a chicken, or other animal) is infected by two different strains of the influenza virus, then it is possible that new assembled viral particles will be created from segments whose origin is mixed ...
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Since hemagglutinin is the major surface protein of the influenza A virus and is essential to the entry process, it is the primary target of neutralizing antibodies. [citation needed] These antibodies against flu have been found to act by two different mechanisms, mirroring the dual functions of hemagglutinin:
Americans are in the throes of flu season in large swaths of the country. Data − from traces in wastewater to hospitalizations − show higher levels of flu virus circulating in most of the U.S ...
Between December 1988 and March 1989, 19 influenza H1N2 virus isolates were identified in 6 cities in China, but the virus did not spread further. [2]A(H1N2) was identified during the 2001–02 flu season (northern hemisphere) in Canada, the U.S., Ireland, Latvia, France, Romania, Oman, India, Malaysia, and Singapore with earliest documented outbreak of the virus occurring in India on May 31 ...