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Despite current guidelines recommending β-blockers and calcium-channel blockers as first-line therapy, there is a lack of evidence demonstrating their superiority over second-line therapies. In this comprehensive review, it is crucial to emphasize that, thus far, neither drugs nor interventions that reduce ischemia have been shown to prolong ...
Angiogenesis inhibitors were once thought to have potential as a "silver bullet" treatment applicable to many types of cancer, but the limitations of anti-angiogenic therapy have been shown in practice. [1] Currently, angiogenesis inhibitors are recognized for their improvement of cancer immunotherapy [2] [3] by overcoming endothelial cell anergy.
Perhexiline (Pexsig) is a prophylactic antianginal agent used primarily in Australia and New Zealand. Perhexiline is thought to act by inhibiting mitochondrial carnitine palmitoyltransferase-1 . This shifts myocardial metabolism from fatty acid to glucose utilisation which results in increased ATP production for the same O 2 consumption and ...
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It is taken twice a day. In 2012, the European Medicines Agency (EMA) finished a review of benefits and risks of trimetazidine and recommended restricting use of trimetazidine-containing medicines to just as an additional treatment of angina pectoris in cases of inadequate control by or intolerance to first-line antianginal therapies. [2]
“An anti-inflammatory diet is the selection of foods that reduce the chronic inflammatory response, while at the same time providing the building blocks for use by anti-inflammatory pathways ...
Credit - Illustration by Christina Lee for TIME. A s the buildup to Valentine's Day intensifies, you might feel the need to prioritize romantic love above all. But there’s a holiday we shouldn ...