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  2. Clostridial necrotizing enteritis - Wikipedia

    en.wikipedia.org/wiki/Clostridial_necrotizing...

    Clostridial necrotizing enteritis (CNE) is a severe and potentially fatal type of food poisoning caused by a β-toxin of Clostridium perfringens, [1] Type C. It occurs in some developing regions, particularly in New Guinea, where it is known as pig-bel.

  3. Clostridium perfringens - Wikipedia

    en.wikipedia.org/wiki/Clostridium_perfringens

    The treatment of Clostridium perfringens infections depends on the type and severity of the condition. For severe infections, such as gas gangrene (clostridial myonecrosis), the primary approach involves surgical debridement of the affected area. This procedure removes devitalized tissue where bacteria grow, which limits the spread of the ...

  4. Clostridium perfringens alpha toxin - Wikipedia

    en.wikipedia.org/wiki/Clostridium_perfringens...

    This toxin has been shown to be the key virulence factor in infection with C. perfringens; the bacterium is unable to cause disease without this toxin. [1] Further, vaccination against the alpha toxin toxoid protects mice against C. perfringens gas gangrene. [2]

  5. Carbapenem-resistant enterobacteriaceae - Wikipedia

    en.wikipedia.org/wiki/Carbapenem-resistant_enter...

    An infection control plan was implemented at the Kaplan Medical Center in Israel to control a hospital outbreak of carbapenem-resistant K. pneumoniae. The comprehensive plan included guidelines for cohorting patients in separate locations, cleaning with 1,000 ppm hypochlorite , screening for isolates from rectal swabs, and distribution of ...

  6. Clostridium enterotoxin - Wikipedia

    en.wikipedia.org/wiki/Clostridium_enterotoxin

    The major virulence factor of C. perfringens is the CPE enterotoxin, which is secreted upon invasion of the host gut, and contributes to food poisoning and other gastrointestinal illnesses. [3] It has a molecular weight of 35.3 kDa, and is responsible for the disintegration of tight junctions between epithelial cells in the gut. [ 6 ]

  7. Gas gangrene - Wikipedia

    en.wikipedia.org/wiki/Gas_gangrene

    The key Clostridium septicum virulence factor is a pore-forming toxin called alpha-toxin, though it is unrelated to the Clostridium perfringens alpha-toxin. Clostridium sordellii can also produce two major toxins: all known virulent strains produce the essential virulence factor lethal toxin (TcsL), and a number also produce haemorrhagic toxin ...

  8. Select agent - Wikipedia

    en.wikipedia.org/wiki/Select_agent

    – The FSAP is composed jointly of the Centers for Disease Control and Prevention/Division of Select Agents and Toxins and the Animal and Plant Health Inspection Service/Agriculture Select Agent Services, and oversees the possession, use and transfer of biological select agents and toxins. "National Science Advisory Board for Biosecurity (NSABB)".

  9. Clostridium - Wikipedia

    en.wikipedia.org/wiki/Clostridium

    Clostridium is a genus of anaerobic, Gram-positive bacteria.Species of Clostridium inhabit soils and the intestinal tracts of animals, including humans. [1] This genus includes several significant human pathogens, including the causative agents of botulism and tetanus.