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Vasoconstrictors are also used clinically to increase blood pressure or to reduce local blood flow. Vasoconstrictors mixed with local anesthetics are used to increase the duration of local anesthesia by constricting the blood vessels, thereby safely concentrating the anesthetic agent for an extended duration, as well as reducing hemorrhage. [4] [5]
A cerebral vasodilator is a drug which acts as a vasodilator in the brain. [1] [2] They are used to improve blood flow in people with cerebrovascular insufficiency and to treat neurological disorders secondary to this condition. [2] A number of different cerebral vasodilators exist.
This area of the skin will become warmer because of vasodilation (loss of vasoconstriction). [5] Depression of the vasomotor center of the brain can cause the loss of vasomotor tone of blood vessels, resulting in massive dilatation of veins. This will result in a condition called as neurogenic shock. [6]
Vascular resistance is the resistance that must be overcome for blood to flow through the circulatory system.The resistance offered by the systemic circulation is known as the systemic vascular resistance or may sometimes be called by another term total peripheral resistance, while the resistance caused by the pulmonary circulation is known as the pulmonary vascular resistance.
Most side effects are direct consequences of the vasodilation and the resultant low blood pressure. They include headache ("nitrate headache") resulting from the widening of blood vessels in the brain, reflex tachycardia (fast heart rate), flush, dizziness, nausea and vomiting. These effects usually subside after a few days if the treatment is ...
Arteriolar vasodilators are substances or medications that preferentially dilate arterioles. When used on people with certain heart conditions, it causes a phenomenon known as the cardiac steal syndrome. [citation needed] Arteriolar vasodilators increase intracapillary pressure, which causes fluid to enter the tissues, leading to vasodilatory ...
Vasodilation, also known as vasorelaxation, is the widening of blood vessels. [1] It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins , large arteries , and smaller arterioles . [ 2 ]
Diazoxide [1] vasodilator used for hypertension, smooth muscle relaxing activity; Minoxidil [2] vasodilator used for hypertension, also used to treat hair loss; Nicorandil [3] vasodilator used to treat angina; Pinacidil [4] Retigabine, [5] [6] an anticonvulsant; Flupirtine, analgesic with muscle relaxant and anticonvulsant properties