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These side effects may occur in as many as 90% of men treated with bicalutamide monotherapy, [29] but gynecomastia is generally reported to occur in 70 to 80% of patients. [30] In the EPC trial, at a median follow-up of 7.4 years, breast pain and gynecomastia respectively occurred in 73.6% and 68.8% of men treated with 150 mg/day bicalutamide ...
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
Hepatitis (liver swelling) Stomatitis (mouth swelling) Liver failure; Pulmonary oedema (fluid in the lungs) Gastrointestinal bleeding; Pulmonary embolism; Myocardial ischaemia (lack of blood supply to the heart muscles) Speech disorders; Haemoglobin decrease; Proteinuria (protein in the urine; usually indicative of kidney damage)
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Conjunctivitis, also known as pink eye or Madras eye, [4] [5] is inflammation of the conjunctiva and the inner surface of the eyelid. [6] It makes the eye appear pink or reddish. [1] Pain, burning, scratchiness, or itchiness may occur. [1] The affected eye may have increased tears or be "stuck shut" in the morning. [1] Swelling of the sclera ...
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Intravitreal injection was first mentioned in a study in 1911, in which the injection of air was used to repair a detached retina. [6] [7] [8] There were also investigations evaluating intravitreal antibiotics injection using sulfanilamide and penicillin to treat endophthalmitis in the 1940s, yet due to the inconsistency of results and safety concerns, this form of drug delivery was only for ...
Chemosis is the swelling (or edema) of the conjunctiva. The term derives from the Greek words cheme and -osis, cheme meaning cockleshell due to the swollen conjunctiva resembling it, and -osis meaning condition. [1] The swelling is due to the oozing of exudate from abnormally permeable capillaries. In general, chemosis is a nonspecific sign of ...
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